Bioinformatics
Preliminary / workflow-support bioinformatics: analysis-workflow framing, sample / metadata readiness review, QC / pipeline review, pathway / result interpretation, differential-analysis framing, and biological reproducibility memo. PRELIMINARY ONLY — does NOT execute real pipelines, interface with raw data, or produce regulated clinical interpretation. Not a substitute for a trained bioinformatician / biostatistician / clinical geneticist, accredited laboratory (CAP / CLIA / ISO 15189), or IRB-approved clinical reporting.
Analysis Workflow Framing
StandardCanonical step list vs declared steps by assay (RNA-seq bulk / single-cell, WGS / WES, ChIP-seq / ATAC-seq, methylation, proteomics, metabolomics, 16S / metagenomics, variant-calling). Workflow-level framing only.
⏱ 3-6 minutes
Sample / Metadata Readiness
StandardSample sheet readiness review — group / batch / date / covariate presence, imbalance, and batch × group confounding detection. Flags missing metadata and underpowered groups.
⏱ 3-6 minutes
QC / Pipeline Review
StandardAssay-specific QC checklist review (FastQC, alignment rate, TSS enrichment, FRiP, coverage, bisulfite conversion, PSM FDR, etc.) vs declared QC and optional measured values. Heuristic thresholds — NOT clinical cutoffs.
⏱ 3-6 minutes
Pathway / Result Interpretation
StandardInterpretation memo over declared enrichment results (FDR filter, small-overlap flag, source diversity). Does NOT re-run enrichment.
⏱ 3-6 minutes
Differential Analysis Framing
StandardRecommended statistical approach + tool by data type (RNA-seq counts / microarray / proteomics / metabolomics / ATAC peaks / methylation / 16S) with sample-size and batch-adjustment flags.
⏱ 3-6 minutes
Biological Reproducibility Memo
StandardReproducibility practice coverage by share-mode (internal / collaborator / public / clinical): tool versions, reference genome, pipeline versioning, raw-data deposit, IRB, clinical SOP, QC archive. Advisory — does NOT audit claims.
⏱ 3-6 minutes